Tests are HSA & FSA accepted

Longevity & Optimization Home Test Kit

$299

The Longevity & Optimization Home Test Kit tracks the markers most tied to healthy aging, so you can optimize stress, hormones, and inflammation over time. It measures 5 markers — Cortisol, DHEA-S, HS-CRP (inflammation), Testosterone, and Vitamin D — ideal for proactive, performance-minded adults. Collected at home in minutes with a premium self-collection device — no clinic visit and no traditional needle stick — then mailed back in prepaid packaging. Physician critical-value review included at no extra cost: a licensed physician reviews your results solely to identify any critical value — an out-of-range result that may be concerning — and if one is found, you’re notified directly so you can seek further medical evaluation. Knowingly Healthy and Test Smartly Labs do NOT interpret, diagnose, treat, or recommend any medical treatment; the physician’s role is strictly limited to flagging critical values. Your results are provided for informational and wellness purposes only and are not a substitute for professional medical advice — you should consult your own medical professional to interpret your results and decide on any next steps. (Test-ordering requirements vary by state; where a physician order is required, it’s arranged for you.) Part of the Knowingly Healthy line, powered by Test Smartly Labs — a direct-access laboratory with 15+ years of trusted service, physical patient locations, and live customer support. Unlike marketing companies that broker your sample to third-party labs, Knowingly Healthy is real lab medicine, processed at a top reference laboratory.

  • Measures Cortisol, your primary stress hormone linked to aging and recovery
  • Measures DHEA-S, an energy and vitality-supporting hormone that declines with age
  • Measures HS-CRP, a key marker of chronic inflammation linked to aging
  • Measures Testosterone, which affects muscle mass, energy, and mood
  • Measures Vitamin D, linked to bone density, immunity, and healthy aging
  • In case of a critical-value result, a licensed physician checks it, and you're notified directly
  • Near-painless at-home collection, no clinic visit needed
  • Fast Results within a few days

Feel the difference of truly knowing your health.

Professional Home Testing

CLIA-certified lab analysis through discreet home kits with comprehensive results.

Complete Privacy & Speed

Results arrive via HIPAA-compliant secure portal within 24-48 hours.

Simple Four-Step Process

Order kit online, collect sample at home, mail it back, access your results.

Trusted Since 2011

We’ve served 30,000+ customers with 97% satisfaction rating.

What We Test For in the Longevity & Optimization Home Test Kit

biomarkers for home health test kit
Your primary stress hormone. Long-term imbalances are linked to accelerated aging, poor sleep, and reduced recovery.
A hormone that supports energy and vitality, and naturally declines with age.
Detects low-grade chronic inflammation, which is linked to cardiovascular disease and accelerated aging.
influences muscle mass, energy, mood, and bone density — all of which are important for long-term vitality in both men and women.
supports bone density, immune resilience, and healthy aging.

How It Works

Order Kit

Choose the option that meets your specific needs. Orders placed before 2 pm CT typically ship the same day.

Collect Sample

Follow the clear step-by-step instructions included in your kit—most collections take just minutes to complete.

Mail Sample

Secure your sample according to the enclosed instructions and mail it back using the pre-paid shipping label.

Access Results

You’ll receive a notification when your results are ready to view in our secure online portal.

Frequently Asked Questions

Your kit includes everything you need for an at-home sample collection, along with simple step-by-step instructions. Once collected, you’ll send your sample to the lab using the prepaid return packaging provided.

Yes, cortisol and testosterone are typically highest in the morning, so testing between 7–10 AM is recommended for the most accurate results.

Results are typically available within 3- 4 working days after the lab receives your sample.

No. The kit uses a near-painless at-home collection method; no needles or clinic visit required.

In case of a critical-value result, a licensed physician checks it at no extra cost, and you’re notified directly. This service is for testing purposes only and doesn’t include medical interpretation, diagnosis, or advice.

This test is intended for adults. Recent illness or infection may temporarily raise HS-CRP levels, and those on hormone therapy or corticosteroid medications should be aware these can affect results.

If a result falls outside the normal range, your report will flag it clearly. For critical values, you’re notified directly so you can follow up with your own doctor.

Yes, all results are encrypted and accessible only to you and the overseeing physicians, in accordance with HIPAA regulations.